Prof. Dr. Semra KAHRAMAN
IVF ve Üreme Genetiği Merkezi Başkanı
Prof. Dr. Semra Kahraman Hacettepe Üniversitesi Tıp Fakültesinden 1981 yılında mezun olmuş ve Ankara Üniversitesi Tıp Fakültesinde Kadın Hastalıkları ve Doğum ihtisasını 1989 yılında tamamlamıştır. 1991 yılında Norveç’te Oslo Üniversitesi ve Haugesund Fertility Center’da 1 yıl süre ile IVF konusunda çalışmalar yapmış ve 1993 yılında Ankara’da Sevgi Hastanesi IVF Merkezi’ni kurmuştur.
1994 yılında AÜTF Kadın Hastalıkları ve Doğum Anabilim Dalı’ndan doçentlik unvanını almıştır. Türkiye’de ilk kez ICSI tekniğini uygulamış ve ilk gebelikleri elde etmiştir. 1996–1997 yılları arasında Amerika Birleşik Devletleri’nde sırayla Cornell Medical Center ve Reproductive Genetics Institute’de IVF Preimplantasyon Genetik Tanı (PGT) konularında çalışmalarda bulunmuştur. Embriyo dondurma teknikleri ve PGT yöntemlerinin ülkemizdeki ilk uygulayıcısı olmuş ve ilk gebelikleri elde etmiştir. Tek Gen hastalıkları için PGT ve embriyolarda HLA tiplemesini Türkiye'de ilk kez uygulayan kişi olmuştur.
2000 yılında İstanbul’da Memorial Hastanesi IVF ve Üreme Genetiği Merkezini kurmuştur. 2003 yılında embriyonik kök hücre çalışmalarını Türkiye’de ilk kez başlatarak, 11 adet uluslararası kayıtlı embriyonik kök hücre dizisinin eldesini sağlamıştır.
2004 yılında Yeditepe Üniversitesi Kadın Hastalıkları ve Doğum anabilim Dalı’nda Profesörlük unvanını almıştır. Preimplantasyon Genetik Tanı International Society (PGDIS) kurucu üyesi ve yönetim kurulu üyesidir. The American Journal of Human Genetics, Human Reproduction, Fertility Sterility, Journal of Assisted Reproduction and Genetics (JARG) ve RBM Online dergilerinde bilimsel hakemlik yapmaktadır.
2008 yılında Üreme Sağlığı ve İnfertilite Derneği (TSRM) tarafından Yaşam Boyu Başarı ve Onur Ödülü ile ödüllendirilmiştir. Basılmış 3 kitabı ve çok sayıda ulusal ve uluslararası makalesi mevcuttur. Halen çalışmakta olduğu İstanbul Memorial Hastanesi IVF Merkezi Sağlık Bakanlığı tarafından seçilmiş Eğitim Merkez’lerinden birisidir.
2011 yılında ABD'de yapılan toplantıda oy birliği ile Preimplantasyon Genetik Tanı International Society (PGDIS)'nin 2013 - 2015 dönem başkanlığına seçilmiştir. 2017 - 2018 yılları arasında American Society of Reproductive Medicine, Preimplantation Genetic Diagnosis Special Interest Group başkanlığı görevini gerçekleştirmiştir.
Publications
International-Peer Reviewed Journals
National Peer-reviewed Journals
Books
International Book Chapters
National Book Chapters
Presentations in International Congresses (as invited)
erator). Preimplantation Genetic Testing 1. ASRM 74th Scientific Congress. Denver, United States of America. October 6-10, 2018.
(2018) Semra Kahraman (Invited speaker). Interactive Session: Is Minimal Stimulation In Vitro Fertilization (IVF) Superior to Standard IVF? Denver, United States of America. October 6-10, 2018.
(2018) Semra Kahraman (Invited speaker). Preimplantaion Genetic Testing for Aneuploidy (PGT-A) in Low, Normal and Hyper Responders. Denver, United States of America. October 6-10, 2018.
(2018) Semra Kahraman (Moderator). Mosaicism and sub-chromosomal variations. 17th International Conference on Preimplantation Genetics. Bangkok, Thailand, May 3-6, 2018
(2018) Semra Kahraman (Invited speaker). PGT-A in Low, Normal and Hyper Responders. 17th International Conference on Preimplantation Genetics. Bangkok, Thailand, May 3-6, 2018
(2018) Semra Kahraman (Invited speaker) Clinical aspects of successful PGT. PGDIS Hands-On Workshop on PGT For Genetic and Chromosomal Disorders by Trophectoderm Biopsy, Istanbul, TURKEY, April 30, 2018.
(2017) Semra Kahraman and Andria Besser. (Moderator). Reproductive Genetics - PGT Outcomes and Counseling. American Society of Reproductive Medicine (ASRM) Scientific Congress and Expo 2017
(2017) Semra Kahraman (Invited speaker).The effect of follicle size and homogeneity of follicular development on the morphokinetics of human embryos and on the cumulus cell gene expression. 19th World Congress on In Vitro Fertilization in conjunction with VI. Society of Reproductive Medicine and Surgery Congress, October 4 - 8, 2017, Antalya, Turkey.
(2017) Semra Kahraman (Invited speaker). Do follicle size and homogenity of follicular development affect gene expression in cumulus cells and the morphokinetics of human embryos? Bringing Innovation to Life. Meet the Grant for Fertility Innovation Awards Winners. Tuesday, July 4 & Wednesday, July 5, 2017, Geneva, Switzerland
(2017) Semra Kahraman (Invited speaker). Blastocyst Preimplantation Genetic Screening (PGS) as the key in optimizing the outcomes. European Society of Human Reproduction and Embryology (ESHRE), May 5-6, 2017, Athens
(2017) Semra Kahraman (Invited speaker). When to transfer? Fresh vs. deferred transfer. 16th International Conference on Preimplantation Genetic Diagnosis. March 26 - 29, 2017, Spain
(2016) Semra Kahraman (Invited speaker). PGD and Ovarian Reserve: which patients benefit more? 15th International Conference on Preimplantation Genetic Diagnosis. 08 - 11 May 2016 / Italy, Bologna
(2016) Semra Kahraman (Chairman). Clinical impact of PGD for aneuploidy. 15th International Conference on Preimplantation Genetic Diagnosis. 08 - 11 May 2016 / Italy, Bologna
(2016) Semra Kahraman (Chairman). Excellence in ART: Clinical and Laboratory Perspectives. Cappadocia, Turkey. April 29 – 30, 2016.
(2016) Semra Kahraman (Invited speaker). Ovarian Reserve and PGD Results. XIV Annual Meeting of the Mediterranean Society for Reproductive Medicine (MSRM).Izmir, Turkey, April 21-24, 2016.
(2015) Semra Kahraman (Invited speaker). The Role of rhCG in Ovarian Stimulation Programs. “Reproductive Technologies Today and Tomorrow” XXV International Conference, Russian Society of Reproductive Medicine. September, 10 – 12, 2015
(2015) Semra Kahraman (Invited speaker). Follow-up HLA Compatible Transplantation after PGD. 14th International Conference on Preimplantation Genetic Diagnosis (PGD), Chicago, Illinois, USA, 11-13 May, 2015
(2015) Semra Kahraman (Invited speaker). Clinical Embryology and PGD outcome. 14th International Conference on Preimplantation Genetic Diagnosis (PGD), Chicago, Illinois, USA, 11-13 May, 2015
(2015) Semra Kahraman (Chairman). Clinical aspects of successful PGD. Hands-on Workshop on PGD for Genetic & Chromosomal Disorders by Blastocyst Biopsy, May 7-9, 2015, Istanbul, Turkey
(2015) Semra Kahraman (Invited speaker). Preimplantation Genetic Diagnosisi, Current Practise in Turkey: European Society of Human Genetics, Course in Collaboration with The Public and Professional Policy Committee, of the European Society of Human Genetics, February 12-13, Istanbul, Turkey
(2014) Semra Kahraman (Invited speaker). Clinical aspects of successful PGD. Preimplantation Genetic Diagnosis International Society (PGDIS) Annual Meeting, Canterbury, UK, 29th April – 2nd May 2014
(2013) Semra Kahraman (Chairman). Preimplantation Genetic Diagnosis. 69th Annual Meeting of the ASRM conjoint with the 21st Meeting of the International Federation of Fertility Societies (IFFS). Boston, Massachusetts, October 12-17, 2013
(2013) Semra Kahraman (Invited speaker). PGD for Genetic Disorders and HLA typing. 17th World Congress on In Vitro Fertilization (ISIVF 2013) - Tunisia, September 4-7, 2013
(2013) Semra Kahraman (Invited speaker). Symposuim Merck Serono. New methods: how to improve laboratory outcomes. 17th World Congress on In Vitro Fertilization (ISIVF 2013) - Tunisia, September 4-7, 2013
(2013) Semra Kahraman (Chairman). Innovation in ART Laboratory. 17th World Congress on In Vitro Fertilization (ISIVF 2013) - Tunisia, September 4-7, 2013
(2013) Semra Kahraman (Chairman). Clinical Aspects of PGD. 12th International Preimplantation Genetic Diagnosis, 8 – 11th May 2013, Istanbul, Turkey
(2013) Semra Kahraman (Invited speaker). PGD for HLA: Clinical outcomes of HLA compatibletransplantation following PGD. 12th International Preimplantation Genetic Diagnosis, 8 – 11th May 2013, Istanbul, Turkey
(2013) Semra Kahraman (Invited speaker). Fertilite koruyucu yaklaşımlar. Meme Kanserinde Yeni Yaklaşımlar Eğitim Toplantısı. İstanbul Kongre Merkezi. January 19 – 20, 2013, Istanbul, Turkey
(2012) Semra Kahraman (Invited speaker). Yaşamı tehdit eden genetik hastalıkların önlenmesi. Science for Peace / Barış için Bilim. Haliç Kongre Merkezi. 03 – 04 Ekim 2012, İstanbul, Turkey
(2012) Semra Kahraman (Chairman). Selected oral communication session: Session 16: Embryology – Embryo in motion. European Society of Human Reproduction & Embryology (ESHRE). July 2, 2012, Harbiye Auditorium, Istanbul, Turkey
(2012) Semra Kahraman (Chairman). Merck Serono Symposium on: Innovation and technologies in ART to become best in class in take home baby rate. 28th Annual Meeting. . European Society of Human Reproduction & Embryology (ESHRE). July 2, 2012, Harbiye Auditorium, Istanbul, Turkey
(2012) Semra Kahraman (Chairman). Advanced Course in Human Reproduction and Embryology. Serono Symposia International Foundation (SSIF). Istanbul, Turkey – June 30, 2012.
(2012) Semra Kahraman (Invited speaker). PGD and HLA matching: a clinical update. 11th International Conference on Preimplantation Genetic Diagnosis. Preimplantation Genetics Diagnosis International Society (PGDIS), Bregenz, Austria, May 16 – 19, 2012
(2012) Semra Kahraman (Chairman). Advanced topics in clinical PGD. 11th International Conference on Preimplantation Genetic Diagnosis. Preimplantation Genetics Diagnosis International Society (PGDIS), Bregenz, Austria, May 16 – 19, 2012
(2011) S. Kahraman. (Invited speaker). Novel Approaches to Preserving Fertility in Cancer Patient. 2nd Mediterranean Multidisiplinary Oncology Forum Congress (MMOF 2011). İstanbul, Turkey, 17 –20 November 2011
(2011) Semra Kahraman. (Invited speaker). PGD in single gene disorders and HLA typing. VITA-NOVA, Bratislava, Slovakya, 16 Eylül 2011
(2011) S. Kahraman. (Invited speaker). PGD, Non Invasive and Other Advances in the prevention of Haemoglobin Disorders. The 12th International Conference on Thalassemia and the Haemoglobinopathies (TIF 2011), 11 – 14 Mayıs 2011, Antalya
(2011) S. Kahraman (Chairman). Session 1: Successful IVF. Transatlantic Reproductive Technologies Network (TARTEN). 14 – 17 April 2011, Istanbul, Turkey
(2011) S.Kahraman (Invited speaker). Techniques for preservation of fertility. 5th AAGL International Congress on Minimally Invasive Gynecology in conjunction with Turkish Society of Gynecological Endoscopy (TSGE) 4th Annual Scientific Meeting(2011).
(2010) S.Kahraman (Invited speaker). Optimal clinical management of PGD patient. International Consensus Meeting on Embryo Transfer & Pre-Congress Workshop on Intrauterine Insemination, December 2–5, 2010, Lavasa, Maharashtra India
(2010) R.Frydman, S.Kahraman (Chairman). Session 8: NON-INVASIVE ASSESSMENT OF OOCYTES AND EMBRYOS II. 10th International Congress Preimplantation Genetic Diagnosis. May 5-8, 2010, Montpellier, France
(2010) S.Kahraman (Invited speaker). PGD for male infertility. 10th International Congress Preimplantation Genetic Diagnosis. May 5-8, 2010, Montpellier, France
(2010) S. Kahraman (Chairman). Session 1: Physiology of Human Reproduction: New Insights. ART: experimental bases for improving outcomes for the benefit of patients. Foundation Serono Symposia International. February 19 – February 20, 2010, Istanbul
(2009) S. Kahraman. (Invited speaker and chairman). PGS: is it the correct answer to the right question? Fertility treatment: from the past to the future. October 2–3, 2009, Prague, Czech Republic
(2009) S. Kahraman. (Invited speaker and chairman). PGD Impact on Reproductive Medicine. 9th International Conference on Preimplantation Genetics. Miami, Florida USA, April 23 – 25, 2009
(2008) S. Kahraman. (Invited speaker). Paternal influences on embriyo development. 7th Anual Meeting of The Mediterranean Society for Reproductive Medicine. Tunisia, 15 – 18 May, 2008.
(2008) S. Kahraman. (Invited speaker). Improved PGD test and clinical applications. 7th Anual Meeting of The Mediterranean Society for Reproductive Medicine. Tunisia, 15 – 18 May, 2008.
(2008) S. Kahraman. (Chairman). PGD ART DATA & SAFETY EPIGENETICS. 8th International Symposium on Preimplantation Genetic Diagnosis. Barcelona, Spain, 23 – 26 April 2008.
(2008) S. Kahraman. (Invited speaker). Male Factor. 8th International Symposium on Preimplantation Genetic Diagnosis. Barcelona, Spain, 23 – 26 April 2008.
(2008) S. Kahraman. (Invited speaker). Clinical Aspects of PGD. Hands-On Workshop on PGD of Genetic & Chromosomal Disorders by Blastomere and Trophectoderm Biopsy. Istanbul Memorial Hospital, 28 – 30 April 2008, Istanbul, Turkey.
(2007) S. Kahraman. (Invited speaker). Preimplantation diagnosis for selecting HLA compatible embryos. 14th Annual Meeting Middle East Fertility Society, Antalya. 31 Oct – 03 Nov, 2007.
(2007) S. Kahraman. (Invited speaker). TC’de Preimplantasyon Genetiği. KKTC Talasemi Çalıştayı. Lefkoşa, KKTC, November 10, 2007.
(2007) S. Kahraman. (Invited speaker). Aneuploidy and embryo development. 7th International Symposium on Preimplantation Genetics, 13-16 June, 2007, Melbourne, Australia.
(2007) S. Kahraman. (Invited speaker). PGD for selecting HLA compatible embryos. 19th IFFS Congress on Fertility and Sterility World Congress. 29th April, 3rd May, Durban, South Africa.
(2007) S. Kahraman. (Invited speaker). The role of LH. 6th Annual Meeting of Mediterranean Society for Reproductive Medicine. 20-23 April 2007, Antalya, Turkey.
(2007) S. Kahraman. (Invited speaker). Overview on the clinical application of PGD. 6th Annual Meeting of Mediterranean Society for Reproductive Medicine. 20-23 April 2007, Antalya, Turkey.
(2006) S. Kahraman. (Invited speaker). PGD for Genetic Diseases. Prevention and Diagnosis of Genetic Diseases. Cagliari, Italy, December 2006.
(2006) S. Kahraman. (Invited speaker). PGD and HLA. Prevention and Diagnosis of Genetic Diseases. Cagliari, Italy, 1 December 2006.
(2006) S. Kahraman. (Invited speaker). Preimplantation genetic diagnosis for chromosomal abnormalities and single gene defects. Ten Years of Puregon, Delivering success: the next decade. 22-23 September 2006, Athens, Greece.
(2006) Kahraman S. (Invited speaker). Endometrial co-culture in cases with repeated implantation failure. 3rd World Congress of the Association of Reproductive Medicine (W.A.R.M.). 27 September - 1 October 2006, Rome, Italy.
(2005) S. Kahraman. (Invited speaker). How to choose the good oocyte, the good spermatozoa and the good embryo? Genetically point of view. National congress of Tunisian Society of Gynecology and Obstetetrics. 9-11th December 2005, Tunusia.
(2005) S. Kahraman. (Invited speaker). Preimplantation genetic diagnosis in severe male infertility. 12th Annual Meeting of the Middle East Fertility Society. 23-26 November, 2005. Luxor, Egypt.
(2005) S. Kahraman. (Invited speaker). Indications of PGD in Male: Genetic Analysis and Expected Outcome. Jordanian Society for Fertility and Genetics. 7th -9th September 2005, Amman, Jordan. 30 Eylül, 2005. Belek, Antalya, Turkiye.
(2005) S. Kahraman. (Invited speaker). Indications of PGD in Male: Genetic Analysis and Expected Outcome. IBO Meeting, 21st Annual Meeting of the European Society of Human Reproduction and Embryology, Copenhagen, Denmark 19-22 June 2005.
(2005) S. Kahraman. (Invited speaker). PGD in avoiding IVF complications. 13th World Congress on in-vitro Fertilization Assisted Reproduction & Genetics, Istanbul, Turkey, May 26-29, 2005.
(2005) S. Kahraman. (Chairman). Ovulation Induction-III (Organon Symposia). 13th World Congress on in-vitro Fertilization Assisted Reproduction & Genetics, Istanbul, Turkey, May 26-29, 2005.
(2005) S. Kahraman. (Invited speaker). Staff development as an important tool increasing the success of IVF program. Pre-Congress Workshop, 13th World Congress on in-vitro Fertilization Assisted Reproduction & Genetics, Istanbul, Turkey, May 26-29, 2005.
(2005). Kahraman S. (Invited speaker). Turkey’s experience of PGD of single gene disorders. Sixth International Symposium on Preimplantation Genetics 2005. London, UK. May 19–21, 2005.
(2005) Kahraman S. (Invited speaker). PGD for Single Gene Disorders and HLA Typing. Ist AFFS (Arab Federation of Fertility Societies) Conference. 27–29 April 2005, Amman, Jordan.
(2005) S. Kahraman. (Invited speaker). Preimplantation Genetic Diagnosis for Single Gene Disorders. 12th World Congress on Human Reproduction. 10-13th March 2005, Venice, Italy.
(2004) Semra Kahraman (Invited speaker). Preimplantation Genetic Diagnosis and HLA genotyping in single gene disorders 14th Annual meeting of Russian Association of Human Reproduction. 26-28 September 2004, Moscow, Russia.
(2004) Semra Kahraman (Invited speaker). Pronuclear morphology scoring and chromosomal status of embryos in severe male infertility. 14th Annual meeting of Russian Association of Human Reproduction. 26-28 September 2004, Moscow, Russia.
(2004) S. Kahraman, (Invited speaker), Necati Fındıklı, Semra Sertyel. Embriyonik kök hücrelerden kardiyomiyosit diferansiasyonu. 1st International Congress on Reproductive Medicine. 22-25 September 2004, İstanbul, Turkey
(2004) S. Kahraman. (Invited speaker). Preimplantation genetic diagnosis of single gene disorders combined with HLA matching. ESTM (European School of Transfusion Medicine) / ITSS (International Thalassemia Summer School) Residential Course. Transfusion Treatment of Thalassaemia and Other Chronic Anemies. 20th - 25th April, 2004, Antalya, Turkey.
(2003) Semra Kahraman (Invited speaker). Preimplantation Genetic Diagnosis. Slovenia Congress of Obstetricians and Gynecologists. 11-13 September 2003, Rogla, Slovenia.
(2003) Semra Kahraman, (Invited speaker). Severe sperm morphological defects and chromosomal abnormality. 19. Jahrestagng der Österreichischen gesselschaft für Reproduktionsmedizin und Endokrinologie, 17-18 October 2003, Bregenz, Austria.
(2003) S. Kahraman, (Invited speaker). Comparison of microdissection and multisampling TESE procedures in azoospermic cases. Dubai International Obs-Gyne and Fertility Conference & Exhibition, October 1-3, 2003, Dubai, UAE.
(2003) S. Kahraman, (Invited speaker). Genetics of severe male infertility. Dubai International Obs-Gyne and Fertility Conference & Exhibition, October 1-3, 2003, Dubai, UAE.
(2003) Semra Kahraman (Invited speaker). Preimplantation genetic diagnosis in aneuploidy testing. The Fourth royan International Research Award, Reproductive Biomedicine. September 2003, Tehran, Iran.
(2003) Semra Kahraman (Invited speaker) Preimplantation genetic diagnosis in single gene disorders. The Fourth royan International Research Award, Reproductive Biomedicine. September 2003, Tehran, Iran.
(2003) S. Kahraman (Invited speaker) PGD impact on IVF efficiency. Fifth International Symposium on Preimplantation Genetics, 5-7 June 2003, Antalya, Turkey.
(2003) S. Kahraman. (Invited speaker). Preimplantation Genetic Diagnosis for Single Gene Disorders and Aneuploidy Testing. Embryologenforum Alpha-Austria 5. Workshop. 29th March, 2003, Linz, Austria.
(2002) S. Kahraman. (Invited speaker). Management of Non-obstructive azoospermia. The IVth Indian Congress on Gynecologic Endoscopy, Infertility & ART. 19-22 December 2002, Jodhpur, India.
(2002) Semra Kahraman. (Invited speaker). Preimplantation genetic diagnosis in cases with abnormal gamete cell morphology. III. International Bulgarian Sterility Congress. Contraception and hormonal therapy. Borovetz, Bulgaria. 10-13 March, 2002.
(2002) S. Kahraman. (Invited speaker). The role of pronuclear scoring in the selection of embryos with beter developmental and implantation capacity. First World Congress of New Advances in Reproductive Technologies and Genetics, 19-22 May 2002, Sabaudia, Italy.
(2002) S. Kahraman. (Invited speaker). Preimplantation genetic diagnosis in embryos developed from gametes with abnormal morphology. First World Congress of New Advances in Reproductive Technologies and Genetics, 19-22 May 2002, Sabaudia, Italy.
(2001) Semra Kahraman, (Invited speaker). Kayhan Yakin, Murat Samli, Faruk Vanlıoğlu, Güvenç Karlıkaya, Semra Sertyel, Ersan Dönmez. A comparative study of three techniques for the analysis of sperm recovery: Touch print cytology, wet preparation and testicular histopathology. Global Congress on Gynecologic Endoscopy, Infertility & ART, December 6-9, 2001, Goa, India.
(1999) S. Kahraman. (Chairman). An analysis of testicular biopsies and sperm recovery rates in non-obstructive azoospermic males. First world conference of A PART, March 13-18, 1999, Venice, Italy.
(1999) Semra Kahraman. (Chairman). Male infertility, ICSI, PESA, TESE & Co. First world conference of A PART. March 13–18, 1999. Venice, Italy.
Presentations in National Congresses (as invited)
Presentations in National Congresses (as invited)
Scientific Meetings and Symposiums
Thesis Advisors
Awards
Oral Presentations in International and National Congresses
Poster Presentations